Manufacturer: Ipca Lab
Pharmaceutical name: Sulfasalazine
Pack: 10 pills (500 mg)
Saaz is a medication primarily utilized for the treatment of ulcerative colitis. It influences a body substance responsible for inflammation, tissue damage, and diarrhea. Saaz is effective for moderate to severe cases of ulcerative colitis and is also prescribed for rheumatoid arthritis in both children and adults who have not found relief with other arthritis treatments.
Saaz is indicated for addressing mild to severe ulcerative colitis and rheumatoid arthritis. Additionally, it has been employed "off label" (not FDA-approved) for conditions such as Crohn's disease and ankylosing spondylitis.
Dosages for adults typically range from 1000 mg to 4000 mg per day, with administration occurring 2 to 4 times daily based on the specific condition being treated. It is recommended to take Saaz with a full glass of water after meals or with food to reduce the likelihood of stomach upset. Patients suffering from kidney issues may require lower doses of sulfasalazine.
Among numerous pregnant women diagnosed with ulcerative colitis or Crohn's disease who received Saaz, there has been no significant increase in the risk of fetal malformations compared to other untreated women with these conditions. Furthermore, no adverse effects were noted in pregnant animals given high doses of sulfasalazine. Therefore, Saaz may be prescribed during pregnancy if the doctor determines that the benefits outweigh the potential risks. However, it is important to highlight that Saaz may decrease sperm count and function in men, with these effects being reversible upon discontinuation of the medication.
Gastrointestinal side effects are common among patients using Saaz, including nausea, vomiting, stomach discomfort, and loss of appetite (anorexia).
Saaz may also lead to changes in skin or urine color, with the appearance of an orange-yellow hue not being a cause for concern.
Patients undergoing Saaz treatment might experience headaches, allergic reactions, and photosensitivity (skin rashes triggered by sunlight), which may necessitate medical evaluation.
Some allergic reactions could escalate from a simple rash to symptoms like difficulty swallowing, blistering, skin peeling or loosening, joint and muscle pain, and unusual fatigue or weakness, possibly accompanied by fever. Severe allergic reactions, although rare, can occur.